即可将网页分享至朋友圈
应物理电子学院宫玉彬教授邀请，6月22日上午，美国宾夕法尼亚大学终身教授任德建来到我校，在物电学院204会议室为师生作题为《动物体内的离子通道基因及生物电信号（Ion Channel Genes and Electrical Signals in Animals）》的精彩报告，报告由魏彦玉教授主持。
报告深入浅出地讲解了神经细胞非选择性钠通道复合体NALCN-UNC80-UNC79，mTOR通路对双孔钠通道的调控机制，TMEM175钾离子通道及其对溶酶体功能的调节作用，细菌钠离子通道NaChBa的功能等内容。结合部分运动能力低下、智力发育异常的临床病例，展示了钠离子通道基因突变导致的临床症状，借此诠释如何通过基因疗法的新技术来治疗此类常规疗法无法治愈的基因疾病。
报告结束后，任教授回答了现场师生的提问，比如引起细胞膜膜电位变化的因素有哪些、引起膜电位变化的氨基酸是否都是碱性的、对比试验中某段基因的剔除操作是在哪个阶段、如何进行的等问题，同时展望了相关技术在医疗领域的前景，如攻克癌症和基因疗法等，在师生中引起热烈反响。
相关链接：
About the speaker: Dr. Ren is a full professor with tenure in the Department of Biology, University of Pennsylvania. He graduated with a B.S. in Electronics from Sichuan University, an M.S. in Underwater Acoustics from the Institute of Acoustics, Chinese Academy of Sciences, and a Ph.D. in Physiology and Biophysics from the State University of New York at Buffalo. He did his postdoctoral training in the Howard Hughes Institute of Medicine, Childrens’ Hospital Boston, Harvard Medical School. His research focus on how cells generate electrical signals used to control physiological functions. His group has discovered and pioneered the studies of several families of ion channel proteins that are important for mammalian fertilization, metabolism, physical endurance and brain function. He has published extensively in top journals including Science, Nature, Cell and Neurons. His seminar will focus on ion channel genes important for brain function and associated genetic variations that cause severe intellectual disability.
编辑：罗莎 / 审核：林坤 / 发布：林坤
